Cannabidiol, or CBD is a non-intoxicating cannabinoid. A growing number of studies suggest that CBD can be an effective and comparatively safe tool for managing aches and pains and minimizing stress.

Potential side effects include dry mouth, reduced appetite and drowsiness.

Cannabinol, or CBN, is a mildly intoxicating cannabinoid that has demonstrated efficacy as a sleep aid or mild sedative.

CBN has few known side effects but when taken in excess may cause nausea or headache. Note that it can also cause a positive THC drug test as it is derived from tetrahydrocannabinolic acid (THC-A).

Melatonin is a naturally occurring hormone produced by the pineal gland in the brain. It’s primarily responsible for regulating the body’s circadian rhythms, which govern the sleep-wake cycle. Its production is influenced by the cycle of light and darkness, with levels peaking during the night to promote sleep and decreasing as daylight approaches to facilitate wakefulness.

Melatonin supplements are commonly used to treat sleep disorders, such as insomnia and jet lag and can aid in adjusting the body’s internal clock, especially for individuals facing sleep schedule disturbances. Beyond its pivotal role in sleep regulation, melatonin possesses antioxidant properties and may also boost the immune system and assist with eye health, and mood regulation.

This Indian herb has been shown to lower cortisol levels, improve sleep and relieve stress and anxiety. It has also been associated with increased muscle strength, primarily in men.

Large doses of ashwaganda can cause diarrhea, vomiting, and, in rare cases, liver problems. Those with grass or nightshade allergies may not tolerate it well. Note that ashwaganda should typically not be taken for more than 3 months at a time.

An essential mineral, magnesium has been shown to help people fall asleep quicker and stay asleep longer. Research suggest that these effects may be most pronounced in older adults. Magnesium may also help to improve mood and heart health.

Magnesium supplements may be unsafe for people who take certain diuretics or antibiotics. In large doses, magnesium may cause diarrhea, nausea, and vomiting. People with kidney issues are at a higher risk of experiencing adverse effects.

PharmaGABA® a natural form of gamma-aminobutyric acid (GABA), a neurotransmitter. Suntheanine® is a 100% pure L-isomer-theanine. Studies have found that when GABA and L-isomer-theanine are used together, they can have enhanced relaxation and sleep-improving effects.

High doses of PharmaGABA® may result in a burning sensation in the throat and could lower blood pressure. High doses of Suntheanine® may cause nausea, headache or dizziness.